Hypertrophic cardiomyopathy (HCM)
A thickening of the heart muscle inherited via the breed's Bengal ancestry. No validated DNA test exists: a candidate Bengal-associated mutation (MYBPC3 A74T) was later found at high frequency in several unrelated breeds and in cats with no heart disease, so it is not used as a diagnostic or breeding test.
What to ask for
A recent echocardiogram report from a veterinary cardiologist for both parents. No DNA test exists for HCM in this breed

